2. Metabolic Disease

Metabolic Disease

Metabolic Disease

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Metabolic diseases is defined by a constellation of interconnected physiological, biochemical, clinical, and metabolic factors that directly increases the risk of cardiovascular disease, type 2 diabetes mellitus, and all cause mortality. Associated conditions include hyperuricemia, fatty liver (especially in concurrent obesity) progressing to nonalcoholic fatty liver disease, polycystic ovarian syndrome (in women), erectile dysfunction (in men), and acanthosis nigricans. Metabolic disease modeling is an essential component of biomedical research and a mandatory prerequisite for the treatment of human disease. Somatic genome editing using CRISPR/Cas9 might be used to establish novel metabolic disease models.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W012875R
    3-Nitropropanoic acid (Standard) 504-88-1
    3-Nitropropanoic acid (Standard) is the analytical standard of 3-Nitropropanoic acid. This product is intended for research and analytical applications. 3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible and orally active inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM. 3-Nitropropanoic acid can induce cell apoptosis[1][2].
    3-Nitropropanoic acid (Standard)
  • HY-W012922R
    2-Methyl-4-pentenoic Acid (Standard) 1575-74-2
    2-Methyl-4-pentenoic Acid (Standard) (2-Methylpent-4-enoic acid (Standard)) is the analytical standard of 2-Methyl-4-pentenoic Acid (HY-W012922). This product is intended for research and analytical applications. 2-Methyl-4-pentenoic Acid (2-Methylpent-4-enoic acid) is an organic acid that can be used as a precursor for synthesizing other compounds. Additionally, changes in the level of 2-Methyl-4-pentenoic Acid may be associated with the susceptibility to schizophrenia and type 2 diabetes.
    2-Methyl-4-pentenoic Acid (Standard)
  • HY-W012926R
    Dihydrouracil (Standard) 504-07-4
    Dihydrouracil (Standard) is the analytical standard of Dihydrouracil. This product is intended for research and analytical applications. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[1][2].
    Dihydrouracil (Standard)
  • HY-W012926S
    Dihydrouracil-13C4,15N2 360769-22-8 98%
    Dihydrouracil-13C4,15N2 is the 13C and 15N labeled Dihydrouracil. Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient.
    Dihydrouracil-13C4,15N2
  • HY-W013014R
    3-Methyl-2-cyclopenten-1-one (Standard) 2758-18-1
    3-Methyl-2-cyclopenten-1-one (Standard) is the analytical standard of 3-Methyl-2-cyclopenten-1-one. This product is intended for research and analytical applications. 3-Methyl-2-cyclopenten-1-one is an endogenous metabolite.
    3-Methyl-2-cyclopenten-1-one (Standard)
  • HY-W013035R
    3-Methyl-2-buten-1-ol (Standard) 556-82-1
    3-Methyl-2-buten-1-ol (Standard) is the analytical standard of 3-Methyl-2-buten-1-ol. This product is intended for research and analytical applications. 3-Methyl-2-buten-1-ol (MBO321) is an orally active endogenous metabolite found in pine trees and is used as a fragrance ingredient in cosmetics and detergents. 3-Methyl-2-buten-1-ol passes cell barrier. 3-Methyl-2-buten-1-ol reduces body weight in rats[1][2][3].
    3-Methyl-2-buten-1-ol (Standard)
  • HY-W013061R
    Propane-1,2,3-triyl tripalmitate (Standard) 555-44-2
    Propane-1,2,3-triyl tripalmitate (Standard) is the analytical standard of Propane-1,2,3-triyl tripalmitate. This product is intended for research and analytical applications. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate (Standard)
  • HY-W013061S
    Propane-1,2,3-triyl tripalmitate-d9 2738376-70-8 98%
    Propane-1,2,3-triyl tripalmitate-d9 is deuterium labeled Propane-1,2,3-triyl tripalmitate. Propane-1,2,3-triyl tripalmitate is an endogenous metabolite.
    Propane-1,2,3-triyl tripalmitate-d9
  • HY-W013063S
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11 98%
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11 is a deuterium labeled 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (HY-W013063). 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine is a phospholipid. 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine can be used for obesity research.
    1,2-Dilinoleoyl-sn-glycero-3-phosphocholine-d11
  • HY-W013078R
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard) 998-07-2
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard) is the analytical standard of (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate. This product is intended for research and analytical applications. (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate is an endogenous metabolite.
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (Standard)
  • HY-W013078S
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54 326495-41-4 ≥99.0%
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54 is deuterium labeled (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate. (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl
    (2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate-d54
  • HY-W013175R
    Uridine 5'-monophosphate disodium salt (Standard) 3387-36-8
    Uridine 5'-monophosphate (disodium salt) (Standard) is the analytical standard of Uridine 5'-monophosphate (disodium salt). This product is intended for research and analytical applications. Uridine 5'-monophosphate (5'-Uridylic acid) disodium salt is an orally active mitochondrial ATP-dependent potassium channel activator that has a protective effect on the heart. Uridine 5'-monophosphate disodium salt can promote the synthesis of CDP-choline and induce apoptosis in intestinal epithelial cells, which is beneficial for gut development and reduces diarrhea.
    Uridine 5'-monophosphate disodium salt (Standard)
  • HY-W013179S
    18-Hydroxycorticosterone-d4 1257742-38-3 98%
    18-Hydroxycorticosterone-d4 is the deuterium labeled 18-Hydroxycorticosterone. 18-Hydroxycorticosterone is a corticosteroid and a derivative of corticosterone, which can lead to serious electrolyte imbalances.
    18-Hydroxycorticosterone-d4
  • HY-W013266R
    N4-Acetylsulfamethoxazole (Standard) 21312-10-7
    N4-Acetylsulfamethoxazole (Standard) is the analytical standard of N4-Acetylsulfamethoxazole. This product is intended for research and analytical applications. N4-Acetylsulfamethoxazole (Acetylsulfamethoxazole) is a metabolite of Sulfamethoxazole (HY-B0322). Sulfamethoxazole is a sulfonamide bacteriostatic antibiotic, used for bacterial infections.
    N4-Acetylsulfamethoxazole (Standard)
  • HY-W013495S
    Porphobilinogen-13C2 98%
    Porphobilinogen-13C2 is the 13C-labeled Porphobilinogen. Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin.
    Porphobilinogen-13C2
  • HY-W013573R
    S-Allyl-L-cysteine (Standard) 21593-77-1
    S-Allyl-L-cysteine (Standard) is the analytical standard of S-Allyl-L-cysteine. This product is intended for research and analytical applications. S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
    S-Allyl-L-cysteine (Standard)
  • HY-W014125R
    Undecanedioic acid (Standard) 1852-04-6
    Undecanedioic acid (Standard) is the analytical standard of Undecanedioic acid. This product is intended for research and analytical applications. Undecanedioic acid is associated with intercellular matrix macromolecules and specifically with elastin.
    Undecanedioic acid (Standard)
  • HY-W014130A
    N-Acetyl-L-arginine dihydrate 210545-23-6 98%
    N-Acetyl-L-arginine (Ac-Arg-OH) dihydrate is an endogenous metabolite.
    N-Acetyl-L-arginine dihydrate
  • HY-W014410R
    Mucic acid (Standard) 526-99-8
    Mucic acid (Standard) is the analytical standard of Mucic acid. This product is intended for research and analytical applications. Mucic acid is an endogenous metabolite.
    Mucic acid (Standard)
  • HY-W014423R
    L-Histidine hydrochloride hydrate (Standard) 5934-29-2
    L-Histidine (hydrochloride hydrate) (Standard) is the analytical standard of L-Histidine (hydrochloride hydrate). This product is intended for research and analytical applications. L-Histidine hydrochloride hydrate (H-His-OH.HCl.H2O) is an endogenous metabolite.
    L-Histidine hydrochloride hydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity